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NCT00070564 · ClinicalTrials.gov registry record · Phase 3
S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer
A Phase 3 study of Breast Cancer, sponsored by SWOG Cancer Research Network.
- Active
- Registry status
- Phase 3
- Development phase
- 3,294
- Enrollment target
- 20
- Study locations
NCT00070564: Active Phase 3 study of Breast Cancer, sponsored by SWOG Cancer Research Network.
NCT00070564 is a Phase 3 study of Breast Cancer that is active but no longer recruiting, run by SWOG Cancer Research Network. The registered enrollment target is 3,294 participants, above the 2,801-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (18% higher). The trial reports 20 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00070564, a Phase 3 study of Breast Cancer, is active but no longer recruiting, sponsored by SWOG Cancer Research Network.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 3,294 participants
- Enrollment target
- 20
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them after surgery may kill any remaining tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating resected breast cancer. PURPOSE: This randomized phase III trial is comparing 2 different regimens of combination chemotherapy to see how well they work in treating patients who have undergone surgery for stage I, stage II, or stage III breast cancer.
Primary Outcome
Disease-free survival (DFS) defined as time from registration (randomization assignment) to first instance of disease recurrence (local, regional, or distant), new breast primary tumor, or death as a result of any cause. The results are entered as disease free survival at year 5.
Conditions Studied
Interventions
- DRUG cyclophosphamide
- DRUG paclitaxel
- DRUG doxorubicin hydrochloride
- BIOLOGICAL pegfilgrastim
- DRUG AC regimen
Study Locations (20)
California
- Alta Bates Summit Comprehensive Cancer Center - Berkeley
- Peninsula Medical Center - Burlingame
- East Bay Radiation Oncology Center - Castro Valley
- Valley Medical Oncology Consultants - Castro Valley - Castro Valley
- Valley Medical Oncology - Fremont
- California Cancer Center - Woodward Park Office - Fresno
- Todd Cancer Institute at Long Beach Memorial Medical Center - Long Beach
- USC/Norris Comprehensive Cancer Center and Hospital - Los Angeles
- Contra Costa Regional Medical Center - Martinez
- Tibotec Therapeutics - Division of Ortho Biotech Products, LP - Marysville
- Memorial Medical Center - Modesto
- El Camino Hospital Cancer Center - Mountain View
Alabama
- Regional Medical Center - Anniston
- UAB Comprehensive Cancer Center - Birmingham
- Providence Cancer Center at Providence Hospital - Mobile
Arizona
- Mayo Clinic Scottsdale - Scottsdale
- Arizona Cancer Center at University of Arizona Health Sciences Center - Tucson
Arkansas
- Hembree Mercy Cancer Center at St. Edward Mercy Medical Center - Fort Smith
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences - Little Rock
Alaska
- Providence Cancer Center - Anchorage
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,294 participants |
| Start Date | 2003-11 |
| Est. Completion | 2027-01 |
| Phase | Phase 3 |
What the registry record for NCT00070564 still lists
NCT00070564 is an interventional study that assigns participants to a tested intervention. Its 3,294 participants enrollment target places it among the larger protocols in the corpus, above the 2,801-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (18% higher).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which cyclophosphamide is the first listed.
NCT00070564 names 20 study sites across 5 states, led by California, Alabama, Arizona.
Frequently Asked Questions
What is clinical trial NCT00070564 about?
NCT00070564 is a clinical study titled "S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer". RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them after surgery may kill any remaining tumor cells. It is not yet known which com...
What is the current status of trial NCT00070564?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 3,294 participants. The study started on 2003-11. Estimated completion is 2027-01.
What conditions does trial NCT00070564 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT00070564?
The interventions under investigation include: cyclophosphamide (DRUG), paclitaxel (DRUG), doxorubicin hydrochloride (DRUG), pegfilgrastim (BIOLOGICAL), AC regimen (DRUG).
Who is sponsoring clinical trial NCT00070564?
This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00070564 being conducted?
This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00070564's enrollment target sits among peer trials
3,294 46th of 1224 higher than 1,179 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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