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NCT00067080 · ClinicalTrials.gov registry record · Phase 2

Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
195
Enrollment target

NCT00067080: Completed Phase 2 study, sponsored by Novartis Pharmaceuticals.

NCT00067080 is a Phase 2 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 195 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00067080, a Phase 2 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
195 participants
Enrollment target

Study Summary

The purpose of this study is to determine if the new orally active iron chelator, ICL670, is as safe as deferoxamine in preventing accumulation of iron in the body while a patient is undergoing repeated blood transfusions.

Interventions

  • DRUG ICL670, deferoxamine

Trial Details

FieldValue
Enrollment Target 195 participants
Start Date 2003-05
Phase Phase 2
Novartis Pharmaceuticals

1,375 total trials

What the finished NCT00067080 record still lists

NCT00067080 is an interventional study that assigns participants to a tested intervention. The registered 195 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% higher).

The record links to 0 conditions, and to 1 intervention - of which ICL670, deferoxamine is the first listed.

NCT00067080 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00067080 about?

NCT00067080 is a clinical study titled "Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions". The purpose of this study is to determine if the new orally active iron chelator, ICL670, is as safe as deferoxamine in preventing accumulation of iron in the body while a patient is undergoing repeated blood transfusions.

What is the current status of trial NCT00067080?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 195 participants. The study started on 2003-05.

What interventions are being tested in trial NCT00067080?

The interventions under investigation include: ICL670, deferoxamine (DRUG).

Who is sponsoring clinical trial NCT00067080?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00067080's enrollment target sits among peer trials

195 350th of 2000 higher than 1,649 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00067080, the US trial registry maintained by the National Library of Medicine. NCT00067080 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.