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NCT00059852 · ClinicalTrials.gov registry record · Phase 2

Erlotinib and Gemcitabine in Treating Patients With Metastatic Breast Cancer Previously Treated With An Anthracycline and/or a Taxane

A Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 2
Development phase
61
Enrollment target

NCT00059852: Completed Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

NCT00059852 is a Phase 2 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 61 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00059852, a Phase 2 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 2
Development phase
61 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy such as gemcitabine work in different ways to stop tumor cells from dividing so they stop growing or die. Erlotinib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Combining gemcitabine with erlotinib may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining gemcitabine with erlotinib in treating patients who have metastatic breast cancer that has been previously treated with an anthracycline and/or a taxane.

Interventions

  • DRUG gemcitabine hydrochloride
  • DRUG erlotinib hydrochloride

Trial Details

FieldValue
Enrollment Target 61 participants
Start Date 2003-06
Est. Completion 2009-01
Phase Phase 2

What the finished NCT00059852 record still lists

NCT00059852 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower).

The record links to 0 conditions, and to 2 interventions - of which gemcitabine hydrochloride is the first listed.

NCT00059852 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00059852 about?

NCT00059852 is a clinical study titled "Erlotinib and Gemcitabine in Treating Patients With Metastatic Breast Cancer Previously Treated With An Anthracycline and/or a Taxane". RATIONALE: Drugs used in chemotherapy such as gemcitabine work in different ways to stop tumor cells from dividing so they stop growing or die. Erlotinib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Combining gemcitabine with erlotinib may kill more tum...

What is the current status of trial NCT00059852?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 61 participants. The study started on 2003-06. Estimated completion is 2009-01.

What interventions are being tested in trial NCT00059852?

The interventions under investigation include: gemcitabine hydrochloride (DRUG), erlotinib hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00059852?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00059852's enrollment target sits among peer trials

61 1026th of 2000 higher than 974 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00059852, the US trial registry maintained by the National Library of Medicine. NCT00059852 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.