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NCT00056537 · ClinicalTrials.gov registry record · Phase 1

ABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic Cancer

A Phase 1 study, sponsored by Active Biotech AB.

Completed
Registry status
Phase 1
Development phase
44
Enrollment target

NCT00056537: Completed Phase 1 study, sponsored by Active Biotech AB.

NCT00056537 is a Phase 1 study that has completed, run by Active Biotech AB. The registered enrollment target is 44 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00056537, a Phase 1 study, has completed, sponsored by Active Biotech AB.

COMPLETED
Registry status
Phase 1
Development phase
44 participants
Enrollment target

Study Summary

The drug ABR-217620 is a combination of two proteins, one that recognizes tumor cells and one that triggers an attack on the tumor cells by activating some white blood cells belonging to the body's normal immune system. In animals, this results in an accumulation of white blood cells in the cancer that can fight the cancer. This study will test how much of the drug can be given to patients with non-small cell lung cancer, renal clear cell carcinoma, or pancreatic cancer without causing unacceptable side effects.

Interventions

  • DRUG ABR-217620

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2003-04
Est. Completion 2006-12
Phase Phase 1
Active Biotech AB

4 total trials

What the finished NCT00056537 record still lists

NCT00056537 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower).

The record links to 0 conditions, and to 1 intervention - of which ABR-217620 is the first listed.

NCT00056537 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00056537 about?

NCT00056537 is a clinical study titled "ABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic Cancer". The drug ABR-217620 is a combination of two proteins, one that recognizes tumor cells and one that triggers an attack on the tumor cells by activating some white blood cells belonging to the body's normal immune system. In animals, this results in an accumulation of white blood cells in the cancer t...

What is the current status of trial NCT00056537?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2003-04. Estimated completion is 2006-12.

What interventions are being tested in trial NCT00056537?

The interventions under investigation include: ABR-217620 (DRUG).

Who is sponsoring clinical trial NCT00056537?

This trial is sponsored by Active Biotech AB, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00056537's enrollment target sits among peer trials

44 1086th of 2000 higher than 901 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00056537, the US trial registry maintained by the National Library of Medicine. NCT00056537 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.