Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00056459 · ClinicalTrials.gov registry record · Phase 3

Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.

A Phase 3 study, sponsored by Novartis.

Completed
Registry status
Phase 3
Development phase
1,168
Enrollment target

NCT00056459: Completed Phase 3 study, sponsored by Novartis.

NCT00056459 is a Phase 3 study that has completed, run by Novartis. The registered enrollment target is 1,168 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (51% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00056459, a Phase 3 study, has completed, sponsored by Novartis.

COMPLETED
Registry status
Phase 3
Development phase
1,168 participants
Enrollment target

Study Summary

To compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal cancer that has spread to other organs and are seeking first chemotherapy treatment

Interventions

  • DRUG Vatalanib

Trial Details

FieldValue
Enrollment Target 1,168 participants
Start Date 2003-02
Phase Phase 3
Novartis

265 total trials

What the finished NCT00056459 record still lists

NCT00056459 is an interventional study that assigns participants to a tested intervention. Its 1,168 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (51% higher).

The record links to 0 conditions, and to 1 intervention - of which Vatalanib is the first listed.

NCT00056459 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00056459 about?

NCT00056459 is a clinical study titled "Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.". To compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal cancer that has spread to other organs and are seeking first chemotherapy treatment

What is the current status of trial NCT00056459?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,168 participants. The study started on 2003-02.

What interventions are being tested in trial NCT00056459?

The interventions under investigation include: Vatalanib (DRUG).

Who is sponsoring clinical trial NCT00056459?

This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00056459's enrollment target sits among peer trials

1,168 237th of 2000 higher than 1,764 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06469788 · 1,170 participants · NA

    Testimonials and Navigation in Rheumatology

  • NCT07009509 · 1,166 participants · NA

    Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping

  • NCT07237048 · 1,164 participants · Phase 2

    Minocycline in Stroke Study at Maimonides

  • NCT04275557 · 1,174 participants

    Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00056459, the US trial registry maintained by the National Library of Medicine. NCT00056459 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.