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NCT00052273 · ClinicalTrials.gov registry record · Phase 1

LY317615 Plus Capecitabine in Treating Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by Jonsson Comprehensive Cancer Center.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target

NCT00052273: Completed Phase 1 study, sponsored by Jonsson Comprehensive Cancer Center.

NCT00052273 is a Phase 1 study that has completed, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00052273, a Phase 1 study, has completed, sponsored by Jonsson Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target

Study Summary

RATIONALE: LY317615 may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth and by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining LY317615 with capecitabine may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining LY317615 with capecitabine in treating patients who have advanced solid tumors.

Interventions

  • DRUG capecitabine
  • DRUG enzastaurin hydrochloride

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2002-12
Est. Completion 2005-10
Phase Phase 1
Jonsson Comprehensive Cancer Center

321 total trials

What the finished NCT00052273 record still lists

NCT00052273 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).

The record links to 0 conditions, and to 2 interventions - of which capecitabine is the first listed.

NCT00052273 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00052273 about?

NCT00052273 is a clinical study titled "LY317615 Plus Capecitabine in Treating Patients With Advanced Solid Tumors". RATIONALE: LY317615 may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth and by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining LY317615 with capecitabine ...

What is the current status of trial NCT00052273?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2002-12. Estimated completion is 2005-10.

What interventions are being tested in trial NCT00052273?

The interventions under investigation include: capecitabine (DRUG), enzastaurin hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00052273?

This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00052273's enrollment target sits among peer trials

16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00052273, the US trial registry maintained by the National Library of Medicine. NCT00052273 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.