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NCT00051831 · ClinicalTrials.gov registry record · NA

Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults

A NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
NA
Development phase
19
Enrollment target

NCT00051831: Completed NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00051831 is a NA study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00051831, a NA study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
NA
Development phase
19 participants
Enrollment target

Study Summary

HIV replication in resting CD4 cells is so minimal that anti-HIV drugs often fail to destroy the virus in these cells. Enfuvirtide, also known as T-20, is a type of anti-HIV drug called a fusion inhibitor. The purpose of this study is to test the ability of a T-20-enhanced treatment regimen to decrease the number of resting CD4 cells that become infected with HIV.

Interventions

  • DRUG Ritonavir
  • DRUG Saquinavir
  • DRUG Tenofovir disoproxil fumarate
  • DRUG Emtricitabine
  • DRUG Enfuvirtide

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2003-10
Est. Completion 2008-05
Phase NA

What the finished NCT00051831 record still lists

NCT00051831 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 5 interventions - of which Ritonavir is the first listed.

NCT00051831 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00051831 about?

NCT00051831 is a clinical study titled "Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults". HIV replication in resting CD4 cells is so minimal that anti-HIV drugs often fail to destroy the virus in these cells. Enfuvirtide, also known as T-20, is a type of anti-HIV drug called a fusion inhibitor. The purpose of this study is to test the ability of a T-20-enhanced treatment regimen to decre...

What is the current status of trial NCT00051831?

This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2003-10. Estimated completion is 2008-05.

What interventions are being tested in trial NCT00051831?

The interventions under investigation include: Ritonavir (DRUG), Saquinavir (DRUG), Tenofovir disoproxil fumarate (DRUG), Emtricitabine (DRUG), Enfuvirtide (DRUG).

Who is sponsoring clinical trial NCT00051831?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00051831's enrollment target sits among peer trials

19 1861st of 2000 higher than 138 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00051831, the US trial registry maintained by the National Library of Medicine. NCT00051831 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.