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NCT00049140 · ClinicalTrials.gov registry record · Phase 2

EF5 Compared With Other Methods of Detecting Oxygen Levels in Tumor Cells of Patients With Head and Neck Cancer

A Phase 2 study, sponsored by David M. Brizel, MD.

Completed
Registry status
Phase 2
Development phase
8
Enrollment target

NCT00049140: Completed Phase 2 study, sponsored by David M. Brizel, MD.

NCT00049140 is a Phase 2 study that has completed, run by David M. Brizel, MD. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00049140, a Phase 2 study, has completed, sponsored by David M. Brizel, MD.

COMPLETED
Registry status
Phase 2
Development phase
8 participants
Enrollment target

Study Summary

RATIONALE: Diagnostic procedures using the drug EF5 to detect the presence of oxygen in tumor cells may help to plan effective treatment for solid tumors. PURPOSE: Phase II trial to compare diagnostic procedures using EF5 to that of other methods of detecting oxygen levels in tumor cells of patients who have head and neck cancer.

Interventions

  • PROCEDURE biopsy
  • OTHER immunohistochemistry staining method
  • OTHER flow cytometry
  • DRUG EF5
  • OTHER bioluminescence

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2002-08
Phase Phase 2
David M. Brizel, MD

2 total trials

What the finished NCT00049140 record still lists

NCT00049140 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 5 interventions - of which biopsy is the first listed.

NCT00049140 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00049140 about?

NCT00049140 is a clinical study titled "EF5 Compared With Other Methods of Detecting Oxygen Levels in Tumor Cells of Patients With Head and Neck Cancer". RATIONALE: Diagnostic procedures using the drug EF5 to detect the presence of oxygen in tumor cells may help to plan effective treatment for solid tumors. PURPOSE: Phase II trial to compare diagnostic procedures using EF5 to that of other methods of detecting oxygen levels in tumor cells of patient...

What is the current status of trial NCT00049140?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2002-08.

What interventions are being tested in trial NCT00049140?

The interventions under investigation include: biopsy (PROCEDURE), immunohistochemistry staining method (OTHER), flow cytometry (OTHER), EF5 (DRUG), bioluminescence (OTHER).

Who is sponsoring clinical trial NCT00049140?

This trial is sponsored by David M. Brizel, MD, which has 2 total clinical trials registered on ClinicalTrials.gov.

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How this trial's enrollment target compares

Where NCT00049140's enrollment target sits among peer trials

8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00049140, the US trial registry maintained by the National Library of Medicine. NCT00049140 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.