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NCT00048308 · ClinicalTrials.gov registry record · Phase 3

Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass

A Phase 3 study, sponsored by Alexion Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
3,000
Enrollment target

NCT00048308 is a Phase 3 study that has completed, run by Alexion Pharmaceuticals. The registered enrollment target is 3,000 participants.

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The verdict

NCT00048308, a Phase 3 study, has completed, sponsored by Alexion Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
3,000 participants
Enrollment target

Study Summary

During a heart bypass procedure, a substance called "complement" is released by the body. This complement causes inflammation, which can lead to side effects such as chest pain, heart attacks, heart failure, or impairment of memory, language and motor skills. The purpose of this study is to find out if the study drug (pexelizumab), which blocks complement release, can reduce such side effects and be taken safely.

Interventions

  • DRUG pexelizumab

Trial Details

FieldValue
Enrollment Target 3,000 participants
Start Date 2002-01
Phase Phase 3

Sponsor

Alexion Pharmaceuticals

162 total trials

What the Registry Record Tells You About NCT00048308

The ClinicalTrials.gov registry entry for NCT00048308 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 3,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alexion Pharmaceuticals, which has 162 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which pexelizumab is the first listed.

NCT00048308 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00048308 about?

NCT00048308 is a clinical study titled "Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass". During a heart bypass procedure, a substance called "complement" is released by the body. This complement causes inflammation, which can lead to side effects such as chest pain, heart attacks, heart failure, or impairment of memory, language and motor skills. The purpose of this study is to find out...

What is the current status of trial NCT00048308?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 3,000 participants. The study started on 2002-01.

What interventions are being tested in trial NCT00048308?

The interventions under investigation include: pexelizumab (DRUG).

Who is sponsoring clinical trial NCT00048308?

This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.