Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00046111 · ClinicalTrials.gov registry record · Phase 1
A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid Tumors
A Phase 1 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT00046111: Completed Phase 1 study, sponsored by GlaxoSmithKline.
NCT00046111 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00046111, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
The purpose of this study is to compare two capsules of topotecan made by slightly different methods. This will be done by giving the drug made by the two different methods to patients orally and testing blood levels.
Interventions
- DRUG topotecan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2001-09 |
| Est. Completion | 2004-04 |
| Phase | Phase 1 |
What the finished NCT00046111 record still lists
NCT00046111 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which topotecan is the first listed.
NCT00046111 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00046111 about?
NCT00046111 is a clinical study titled "A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid Tumors". The purpose of this study is to compare two capsules of topotecan made by slightly different methods. This will be done by giving the drug made by the two different methods to patients orally and testing blood levels.
What is the current status of trial NCT00046111?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2001-09. Estimated completion is 2004-04.
What interventions are being tested in trial NCT00046111?
The interventions under investigation include: topotecan (DRUG).
Who is sponsoring clinical trial NCT00046111?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00046111's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia