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NCT00044707 · ClinicalTrials.gov registry record · Phase 2

Evaluation of an Orally Administered Medication When Taken in Conjunction With Pramlintide

A Phase 2 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 2
Development phase
24
Enrollment target

NCT00044707: Completed Phase 2 study, sponsored by AstraZeneca.

NCT00044707 is a Phase 2 study that has completed, run by AstraZeneca. The registered enrollment target is 24 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00044707, a Phase 2 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 2
Development phase
24 participants
Enrollment target

Study Summary

This is a randomized, single-blind, placebo-controlled, crossover study to examine the effect of pramlintide on the pharmacokinetics of an orally administered medication

Primary Outcome

To determine the effect of pramlintide on the pharmacokinetics of an orally administered concomitant medication (acetaminophen) when administered at various times in relation to subcutaneous (SC) pramlintide dosing. The noncompartmental plasma acetaminophen pharmacokinetic (PK) parameters used in the analyses are defined as follows: AUC(0-12hr): Area under the plasma acetaminophen concentration-time curve. Cmax : The peak acetaminophen concentrationd. Tmax : Duration from the time of acetaminoph

Interventions

  • DRUG Pramlintide acetate

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2002-08
Est. Completion 2002-09
Phase Phase 2
AstraZeneca

1,285 total trials

What the finished NCT00044707 record still lists

NCT00044707 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 1 intervention - of which Pramlintide acetate is the first listed.

NCT00044707 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00044707 about?

NCT00044707 is a clinical study titled "Evaluation of an Orally Administered Medication When Taken in Conjunction With Pramlintide". This is a randomized, single-blind, placebo-controlled, crossover study to examine the effect of pramlintide on the pharmacokinetics of an orally administered medication

What is the current status of trial NCT00044707?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2002-08. Estimated completion is 2002-09.

What interventions are being tested in trial NCT00044707?

The interventions under investigation include: Pramlintide acetate (DRUG).

Who is sponsoring clinical trial NCT00044707?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00044707's enrollment target sits among peer trials

24 1756th of 2000 higher than 217 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00044707, the US trial registry maintained by the National Library of Medicine. NCT00044707 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.