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NCT00043966 · ClinicalTrials.gov registry record · Phase 3

Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects

A Phase 3 study, sponsored by Abbott.

Completed
Registry status
Phase 3
Development phase
200
Enrollment target

NCT00043966: Completed Phase 3 study, sponsored by Abbott.

NCT00043966 is a Phase 3 study that has completed, run by Abbott. The registered enrollment target is 200 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00043966, a Phase 3 study, has completed, sponsored by Abbott.

COMPLETED
Registry status
Phase 3
Development phase
200 participants
Enrollment target

Study Summary

The purpose of this study is to compare the safety, tolerability and antiviral activity between once-daily (QD) and twice-daily (BID) dosing of lopinavir/ritonavir and to further characterize the pharmacokinetics of once-daily dosing of lopinavir/ritonavir.

Interventions

  • DRUG Tenofovir DF
  • DRUG Emtricitabine
  • DRUG Lopinavir/ritonavir

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2002-07
Phase Phase 3
Abbott

181 total trials

What the finished NCT00043966 record still lists

NCT00043966 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (74% lower).

The record links to 0 conditions, and to 3 interventions - of which Tenofovir DF is the first listed.

NCT00043966 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00043966 about?

NCT00043966 is a clinical study titled "Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects". The purpose of this study is to compare the safety, tolerability and antiviral activity between once-daily (QD) and twice-daily (BID) dosing of lopinavir/ritonavir and to further characterize the pharmacokinetics of once-daily dosing of lopinavir/ritonavir.

What is the current status of trial NCT00043966?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 200 participants. The study started on 2002-07.

What interventions are being tested in trial NCT00043966?

The interventions under investigation include: Tenofovir DF (DRUG), Emtricitabine (DRUG), Lopinavir/ritonavir (DRUG).

Who is sponsoring clinical trial NCT00043966?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00043966's enrollment target sits among peer trials

200 1353rd of 2000 higher than 613 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00043966, the US trial registry maintained by the National Library of Medicine. NCT00043966 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.