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NCT00040482 · ClinicalTrials.gov registry record · Phase 2

High Dose Chemo/Radiotherapy and Hematopoietic Stem Cell Transplant for Patients With Multiple Sclerosis

A Phase 2 study, sponsored by Baylor College of Medicine.

Completed
Registry status
Phase 2
Development phase
10
Enrollment target

NCT00040482: Completed Phase 2 study, sponsored by Baylor College of Medicine.

NCT00040482 is a Phase 2 study that has completed, run by Baylor College of Medicine. The registered enrollment target is 10 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00040482, a Phase 2 study, has completed, sponsored by Baylor College of Medicine.

COMPLETED
Registry status
Phase 2
Development phase
10 participants
Enrollment target

Study Summary

Multiple Sclerosis is a disease that may be caused by the immune system reacting against the nervous system. It is possible, that by changing the immune system we can modify the progression of this disease. In this study, we will try to learn whether treatment with a bone marrow transplant (BMT) can help patients with multiple sclerosis. We will also try to learn what the side effects are of this treatment in patients with multiple sclerosis.

Interventions

  • DRUG Cyclophosphamide
  • DRUG MESNA
  • DRUG ATG
  • PROCEDURE Radiation therapy

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 1999-04
Est. Completion 2005-08
Phase Phase 2
Baylor College of Medicine

616 total trials

What the finished NCT00040482 record still lists

NCT00040482 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 4 interventions - of which Cyclophosphamide is the first listed.

NCT00040482 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00040482 about?

NCT00040482 is a clinical study titled "High Dose Chemo/Radiotherapy and Hematopoietic Stem Cell Transplant for Patients With Multiple Sclerosis". Multiple Sclerosis is a disease that may be caused by the immune system reacting against the nervous system. It is possible, that by changing the immune system we can modify the progression of this disease. In this study, we will try to learn whether treatment with a bone marrow transplant (BMT) can...

What is the current status of trial NCT00040482?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 1999-04. Estimated completion is 2005-08.

What interventions are being tested in trial NCT00040482?

The interventions under investigation include: Cyclophosphamide (DRUG), MESNA (DRUG), ATG (DRUG), Radiation therapy (PROCEDURE).

Who is sponsoring clinical trial NCT00040482?

This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00040482's enrollment target sits among peer trials

10 1968th of 2000 higher than 12 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00040482, the US trial registry maintained by the National Library of Medicine. NCT00040482 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.