Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00040157 · ClinicalTrials.gov registry record · Phase 2

Safety and Antiviral Study of ACH-126, 443 (Beta-L-Fd4C) in the Treatment of Adults With HIV Infection and Modestly Detectable Viral Load.

A Phase 2 study, sponsored by Alexion Pharmaceuticals.

Terminated
Registry status
Phase 2
Development phase
60
Enrollment target

NCT00040157: Clinical Trial Phase 2 study, sponsored by Alexion Pharmaceuticals.

NCT00040157 is a Phase 2 study that was terminated before completion, run by Alexion Pharmaceuticals. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00040157, a Phase 2 study, was terminated before completion, sponsored by Alexion Pharmaceuticals.

TERMINATED
Registry status
Phase 2
Development phase
60 participants
Enrollment target

Study Summary

To determine safety and efficacy of ACH-126,443 on the treatment of adults with HIV infection who have modestly detectable viral load while on stable triple combination antiretroviral therapy including 3TC.

Interventions

  • DRUG ACH126-443 (Beta-L-Fd4C)

Trial Details

FieldValue
Enrollment Target 60 participants
Est. Completion 2003-05
Phase Phase 2
Alexion Pharmaceuticals

162 total trials

Why NCT00040157 stopped before completion

NCT00040157 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 1 intervention - of which ACH126-443 (Beta-L-Fd4C) is the first listed.

NCT00040157 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00040157 about?

NCT00040157 is a clinical study titled "Safety and Antiviral Study of ACH-126, 443 (Beta-L-Fd4C) in the Treatment of Adults With HIV Infection and Modestly Detectable Viral Load.". To determine safety and efficacy of ACH-126,443 on the treatment of adults with HIV infection who have modestly detectable viral load while on stable triple combination antiretroviral therapy including 3TC.

What is the current status of trial NCT00040157?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 60 participants. Estimated completion is 2003-05.

What interventions are being tested in trial NCT00040157?

The interventions under investigation include: ACH126-443 (Beta-L-Fd4C) (DRUG).

Who is sponsoring clinical trial NCT00040157?

This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00040157's enrollment target sits among peer trials

60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00576069 · 60 participants

    Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma

  • NCT01297400 · 60 participants · Phase 2

    Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

  • NCT01734122 · 60 participants

    Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

  • NCT01804634 · 60 participants · Phase 2

    Reduced Intensity Haploidentical BMT for High Risk Solid Tumors

Source: ClinicalTrials.gov NCT00040157, the US trial registry maintained by the National Library of Medicine. NCT00040157 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.