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NCT00038441 · ClinicalTrials.gov registry record · Phase 1

Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
39
Enrollment target

NCT00038441: Completed Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT00038441 is a Phase 1 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 39 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (35% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00038441, a Phase 1 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
39 participants
Enrollment target

Study Summary

This is a clinical research study of a new investigational treatment for cancer called "DTI-015" to be given by intratumoral injection. Intratumoral injection is when drug is injected directly into the tumor. This study will help doctors find out what is the best dose level for DTI-015 and if this treatment can shrink tumors without causing severe side effects. The effects of the drug on the patient's quality of life (how the patient feels and what the patient can do) and their mental functions (reasoning and thinking abilities) will also be studied.

Interventions

  • DRUG DTI-015

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 1995-09
Est. Completion 2005-08
Phase Phase 1
M.D. Anderson Cancer Center

2,692 total trials

What the finished NCT00038441 record still lists

NCT00038441 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (35% lower).

The record links to 0 conditions, and to 1 intervention - of which DTI-015 is the first listed.

NCT00038441 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00038441 about?

NCT00038441 is a clinical study titled "Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas". This is a clinical research study of a new investigational treatment for cancer called "DTI-015" to be given by intratumoral injection. Intratumoral injection is when drug is injected directly into the tumor. This study will help doctors find out what is the best dose level for DTI-015 and if this t...

What is the current status of trial NCT00038441?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 39 participants. The study started on 1995-09. Estimated completion is 2005-08.

What interventions are being tested in trial NCT00038441?

The interventions under investigation include: DTI-015 (DRUG).

Who is sponsoring clinical trial NCT00038441?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00038441's enrollment target sits among peer trials

39 1191st of 2000 higher than 804 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00038441, the US trial registry maintained by the National Library of Medicine. NCT00038441 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.