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NCT00032630 · ClinicalTrials.gov registry record · Phase 3

Outcomes Following Myocardial Revascularization: On and Off Cardiopulmonary Bypass

A Phase 3 study, sponsored by US Department of Veterans Affairs.

Completed
Registry status
Phase 3
Development phase
2,203
Enrollment target

NCT00032630: Completed Phase 3 study, sponsored by US Department of Veterans Affairs.

NCT00032630 is a Phase 3 study that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 2,203 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (185% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00032630, a Phase 3 study, has completed, sponsored by US Department of Veterans Affairs.

COMPLETED
Registry status
Phase 3
Development phase
2,203 participants
Enrollment target

Study Summary

Ischemic heart disease is one of the most frequent diagnoses in the VA system. Moreover, 5,819 coronary artery bypass graft (CABG-only) procedures were performed in the VA in Fiscal Year (FY) 1999. Throughout VA and non-VA cardiac surgery programs nationwide, myocardial revascularization is now being performed using two surgical techniques. One technique is performed with cardiopulmonary bypass (CPB) usually with cardioplegic arrest ("on-pump") and the other without CPB on a beating heart ("off-pump"). The overall purpose of this proposed randomized, controlled, clinical trial is to rigorously evaluate the impact of using an on-pump versus off-pump surgical technique for coronary artery bypass graft (CABG-only) procedures (performed with a traditional median sternotomy incision) upon patient clinical outcomes and resource utilization.

Primary Outcome

Short-term end point was a composite of death or major complications (reoperation, new mechanical support, cardiac arrest, coma, stroke, or renal failure requiring dialysis) occuring within 30 days after surgery or before discharge, whichever was later.

Interventions

  • PROCEDURE Coronary artery bypass - on-pump
  • PROCEDURE Coronary artery bypass - off-pump

Trial Details

FieldValue
Enrollment Target 2,203 participants
Start Date 2002-04
Est. Completion 2008-04
Phase Phase 3
US Department of Veterans Affairs

632 total trials

What the finished NCT00032630 record still lists

NCT00032630 is an interventional study that assigns participants to a tested intervention. Its 2,203 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (185% higher).

The record links to 0 conditions, and to 2 interventions - of which Coronary artery bypass - on-pump is the first listed.

NCT00032630 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00032630 about?

NCT00032630 is a clinical study titled "Outcomes Following Myocardial Revascularization: On and Off Cardiopulmonary Bypass". Ischemic heart disease is one of the most frequent diagnoses in the VA system. Moreover, 5,819 coronary artery bypass graft (CABG-only) procedures were performed in the VA in Fiscal Year (FY) 1999. Throughout VA and non-VA cardiac surgery programs nationwide, myocardial revascularization is now bein...

What is the current status of trial NCT00032630?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 2,203 participants. The study started on 2002-04. Estimated completion is 2008-04.

What interventions are being tested in trial NCT00032630?

The interventions under investigation include: Coronary artery bypass - on-pump (PROCEDURE), Coronary artery bypass - off-pump (PROCEDURE).

Who is sponsoring clinical trial NCT00032630?

This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00032630's enrollment target sits among peer trials

2,203 95th of 2000 higher than 1,906 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00032630, the US trial registry maintained by the National Library of Medicine. NCT00032630 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.