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NCT00031681 · ClinicalTrials.gov registry record · Phase 1

7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
41
Enrollment target

NCT00031681: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00031681 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 41 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00031681, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
41 participants
Enrollment target

Study Summary

This phase I trial is studying the side effects and best dose of giving 7-hydroxystaurosporine together with irinotecan hydrochloride in treating patients with metastatic or unresectable solid tumors, including triple-negative breast cancer (currently enrolling only patients with triple-negative breast cancer since 6/8/2007). Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving 7-hydroxystaurosporine together with irinotecan hydrochloride may help kill more cancer cells by making tumor cells more sensitive to the drug.

Interventions

  • OTHER diagnostic laboratory biomarker analysis
  • DRUG irinotecan hydrochloride
  • DRUG 7-hydroxystaurosporine

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2001-12
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00031681

The ClinicalTrials.gov registry entry for NCT00031681 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which diagnostic laboratory biomarker analysis is the first listed.

NCT00031681 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00031681 about?

NCT00031681 is a clinical study titled "7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)". This phase I trial is studying the side effects and best dose of giving 7-hydroxystaurosporine together with irinotecan hydrochloride in treating patients with metastatic or unresectable solid tumors, including triple-negative breast cancer (currently enrolling only patients with triple-negative bre...

What is the current status of trial NCT00031681?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2001-12.

What interventions are being tested in trial NCT00031681?

The interventions under investigation include: diagnostic laboratory biomarker analysis (OTHER), irinotecan hydrochloride (DRUG), 7-hydroxystaurosporine (DRUG).

Who is sponsoring clinical trial NCT00031681?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.