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NCT00028418 · ClinicalTrials.gov registry record · Phase 1

Clofarabine in Chronic Lymphocytic Leukemia

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
100
Enrollment target

NCT00028418: Completed Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT00028418 is a Phase 1 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 100 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00028418, a Phase 1 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
100 participants
Enrollment target

Study Summary

This is a dose-escalation study to determine the maximum tolerated dose and toxic effects of clofarabine in patients with chronic lymphocytic leukemia and other acute leukemias. Clofarabine is a synthesized hybrid nucleoside analog, which is believed to possess the better qualities of fludarabine and chlorodeoxyadenosine, the 2 most active agents against lymphoproliferative disorders. Thus, it is hoped that this drug will be more active and less toxic than similar drugs.

Interventions

  • DRUG Clofarabine

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 1999-02
Est. Completion 2004-03
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT00028418

The ClinicalTrials.gov registry entry for NCT00028418 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Clofarabine is the first listed.

NCT00028418 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00028418 about?

NCT00028418 is a clinical study titled "Clofarabine in Chronic Lymphocytic Leukemia". This is a dose-escalation study to determine the maximum tolerated dose and toxic effects of clofarabine in patients with chronic lymphocytic leukemia and other acute leukemias. Clofarabine is a synthesized hybrid nucleoside analog, which is believed to possess the better qualities of fludarabine an...

What is the current status of trial NCT00028418?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 1999-02. Estimated completion is 2004-03.

What interventions are being tested in trial NCT00028418?

The interventions under investigation include: Clofarabine (DRUG).

Who is sponsoring clinical trial NCT00028418?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.