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NCT00028405 · ClinicalTrials.gov registry record · Phase 1
Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors
A Phase 1 study, sponsored by Light Sciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT00028405: Completed Phase 1 study, sponsored by Light Sciences.
NCT00028405 is a Phase 1 study that has completed, run by Light Sciences. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00028405, a Phase 1 study, has completed, sponsored by Light Sciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
This multi-center photodynamic therapy study plans to treat patients with large tumors in any superficial location, sarcoma, tumors of oral/oro-pharyngeal cavity, tumors with extensive pelvic involvement, or liver metastasis. The treatment is limited to patients that have failed to respond to currently approved methods of treatment. The study involves a single, intravenous administration of an investigational drug, LS11 (previously studied in approximately 80 cancer patients) and the placement of a novel, flexible light delivery catheter inside the tumor by a minor surgical procedure. The activation of LS11 by the light delivery catheter over a period of 1-24 hrs may result in destruction of tumor tissue.
Interventions
- DRUG LS 11(Taporfin Sodium)
- DEVICE Lumaflex Light Delivery Catheter
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2001-11 |
| Est. Completion | 2002-12 |
| Phase | Phase 1 |
What the finished NCT00028405 record still lists
NCT00028405 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 2 interventions - of which LS 11(Taporfin Sodium) is the first listed.
NCT00028405 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00028405 about?
NCT00028405 is a clinical study titled "Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors". This multi-center photodynamic therapy study plans to treat patients with large tumors in any superficial location, sarcoma, tumors of oral/oro-pharyngeal cavity, tumors with extensive pelvic involvement, or liver metastasis. The treatment is limited to patients that have failed to respond to curren...
What is the current status of trial NCT00028405?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2001-11. Estimated completion is 2002-12.
What interventions are being tested in trial NCT00028405?
The interventions under investigation include: LS 11(Taporfin Sodium) (DRUG), Lumaflex Light Delivery Catheter (DEVICE).
Who is sponsoring clinical trial NCT00028405?
This trial is sponsored by Light Sciences, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00028405's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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