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NCT00027703 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
106
Enrollment target

NCT00027703: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00027703 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 106 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00027703, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
106 participants
Enrollment target

Study Summary

This randomized phase II trial is to see if combination chemotherapy works better with or without bevacizumab in treating patients who have malignant mesothelioma. Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or deliver cancer-killing substances to them. It is not yet known if combination chemotherapy works better with or without bevacizumab in treating malignant mesothelioma.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER placebo
  • DRUG cisplatin
  • BIOLOGICAL bevacizumab
  • DRUG gemcitabine hydrochloride

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2001-10
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00027703

The ClinicalTrials.gov registry entry for NCT00027703 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 106 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT00027703 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00027703 about?

NCT00027703 is a clinical study titled "Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma". This randomized phase II trial is to see if combination chemotherapy works better with or without bevacizumab in treating patients who have malignant mesothelioma. Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies, ...

What is the current status of trial NCT00027703?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 106 participants. The study started on 2001-10.

What interventions are being tested in trial NCT00027703?

The interventions under investigation include: laboratory biomarker analysis (OTHER), placebo (OTHER), cisplatin (DRUG), bevacizumab (BIOLOGICAL), gemcitabine hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00027703?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.