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NCT00024245 · ClinicalTrials.gov registry record · Phase 1
10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors
A Phase 1 study, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
NCT00024245: Completed Phase 1 study, sponsored by Memorial Sloan Kettering Cancer Center.
NCT00024245 is a Phase 1 study that has completed, run by Memorial Sloan Kettering Cancer Center. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00024245, a Phase 1 study, has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Probenecid may increase the effectiveness of 10-propargyl-10-deazaaminopterin by making tumor cells more sensitive to the drug. PURPOSE: Phase I trial to study the effectiveness of combining 10-propargyl-10-deazaaminopterin and probenecid in treating patients who have advanced solid tumors.
Interventions
- DRUG pralatrexate
- DRUG probenecid
Trial Details
| Field | Value |
|---|---|
| Start Date | 2001-05 |
| Est. Completion | 2003-04 |
| Phase | Phase 1 |
What the finished NCT00024245 record still lists
NCT00024245 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 0 conditions, and to 2 interventions - of which pralatrexate is the first listed.
NCT00024245 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00024245 about?
NCT00024245 is a clinical study titled "10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Probenecid may increase the effectiveness of 10-propargyl-10-deazaaminopterin by making tumor cells more sensitive to the drug. PURPOSE: Phase I trial to study the effectiveness o...
What is the current status of trial NCT00024245?
This trial is currently completed. It is a Phase 1 study. The study started on 2001-05. Estimated completion is 2003-04.
What interventions are being tested in trial NCT00024245?
The interventions under investigation include: pralatrexate (DRUG), probenecid (DRUG).
Who is sponsoring clinical trial NCT00024245?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
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