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NCT00019864 · ClinicalTrials.gov registry record · Phase 2
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
A Phase 2 study, sponsored by National Cancer Institute (NCI).
- Terminated
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT00019864: Clinical Trial Phase 2 study, sponsored by National Cancer Institute (NCI).
NCT00019864 is a Phase 2 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00019864, a Phase 2 study, was terminated before completion, sponsored by National Cancer Institute (NCI).
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery. Giving chemotherapy after surgery may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving chemotherapy before and after surgery works in treating patients with osteosarcoma.
Interventions
- DRUG cisplatin
- DRUG leucovorin calcium
- BIOLOGICAL filgrastim
- DRUG dexrazoxane hydrochloride
- DRUG doxorubicin hydrochloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2000-03 |
| Est. Completion | 2011-10 |
| Phase | Phase 2 |
Why NCT00019864 stopped before completion
NCT00019864 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 5 interventions - of which cisplatin is the first listed.
NCT00019864 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00019864 about?
NCT00019864 is a clinical study titled "Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery. Giving chemotherapy after surgery may kill more tumor cells. PURPOSE: This phase ...
What is the current status of trial NCT00019864?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2000-03. Estimated completion is 2011-10.
What interventions are being tested in trial NCT00019864?
The interventions under investigation include: cisplatin (DRUG), leucovorin calcium (DRUG), filgrastim (BIOLOGICAL), dexrazoxane hydrochloride (DRUG), doxorubicin hydrochloride (DRUG).
Who is sponsoring clinical trial NCT00019864?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00019864's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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