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NCT00019708 · ClinicalTrials.gov registry record · Phase 1

Geldanamycin Analogue in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
Phase 1
Development phase
45
Enrollment target

NCT00019708: Clinical Trial Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00019708 is a Phase 1 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 45 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00019708, a Phase 1 study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
Phase 1
Development phase
45 participants
Enrollment target

Study Summary

Phase I trial to study the effectiveness of geldanamycin analogue in treating patients who have advanced solid tumors or non-Hodgkin's lymphoma. Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die.

Primary Outcome

DLT are defined as any greater than or equal to grade 3 non-hematologic toxicity (except for alopecia of any grade, grade 3 nausea or vomiting during less than maximal antiemetic therapy, and grade 3 fever in the absence of neutropenia and infection), any grade 4 hematologic toxicity (except for anemia of any grade), or the inability to resume treatment by day 42 (longer than two week delay) because of drug related toxicity.

Interventions

  • DRUG tanespimycin

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 1999-06
Phase Phase 1
National Cancer Institute (NCI)

3,257 total trials

Why NCT00019708 stopped before completion

NCT00019708 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower).

The record links to 0 conditions, and to 1 intervention - of which tanespimycin is the first listed.

NCT00019708 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00019708 about?

NCT00019708 is a clinical study titled "Geldanamycin Analogue in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma". Phase I trial to study the effectiveness of geldanamycin analogue in treating patients who have advanced solid tumors or non-Hodgkin's lymphoma. Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die.

What is the current status of trial NCT00019708?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 1999-06.

What interventions are being tested in trial NCT00019708?

The interventions under investigation include: tanespimycin (DRUG).

Who is sponsoring clinical trial NCT00019708?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00019708's enrollment target sits among peer trials

45 1066th of 2000 higher than 915 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00019708, the US trial registry maintained by the National Library of Medicine. NCT00019708 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.