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NCT00018759 · ClinicalTrials.gov registry record · Phase 4
Treatment Effects on Platelet Calcium in Hypertensive and Depressed Patients
A Phase 4 study, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- Phase 4
- Development phase
NCT00018759: Completed Phase 4 study, sponsored by US Department of Veterans Affairs.
NCT00018759 is a Phase 4 study that has completed, run by US Department of Veterans Affairs. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00018759, a Phase 4 study, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- Phase 4
- Development phase
Study Summary
This study aims to determine if treatment with an SSRI antidepressant medication, paroxetine, is associated with cellular calcium response to serotonin, platelet serotonin receptors, and improvement in mood in depressed patients with or without hypertension. It is hypothesized that platelets of hypertensive patients with depressive symptomatology with be hyper-responsive to serotonin. Additionally, treatment with an SSRI antidepressant is expected to produce a down-regulation of the serotonin receptor with an associated reduction in platelet cytosolic calcium response as well as improved mood.
Interventions
- DRUG paroxetine
- BEHAVIORAL ongoing psychological screening
Trial Details
| Field | Value |
|---|---|
| Start Date | 2001-03 |
| Est. Completion | 2003-10 |
| Phase | Phase 4 |
What the finished NCT00018759 record still lists
NCT00018759 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 0 conditions, and to 2 interventions - of which paroxetine is the first listed.
NCT00018759 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00018759 about?
NCT00018759 is a clinical study titled "Treatment Effects on Platelet Calcium in Hypertensive and Depressed Patients". This study aims to determine if treatment with an SSRI antidepressant medication, paroxetine, is associated with cellular calcium response to serotonin, platelet serotonin receptors, and improvement in mood in depressed patients with or without hypertension. It is hypothesized that platelets of hype...
What is the current status of trial NCT00018759?
This trial is currently completed. It is a Phase 4 study. The study started on 2001-03. Estimated completion is 2003-10.
What interventions are being tested in trial NCT00018759?
The interventions under investigation include: paroxetine (DRUG), ongoing psychological screening (BEHAVIORAL).
Who is sponsoring clinical trial NCT00018759?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
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