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NCT00018200 · ClinicalTrials.gov registry record · Phase 2
Effect of Antidepressants on Back Pain
A Phase 2 study, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- Phase 2
- Development phase
- 130
- Enrollment target
NCT00018200: Completed Phase 2 study, sponsored by US Department of Veterans Affairs.
NCT00018200 is a Phase 2 study that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 130 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00018200, a Phase 2 study, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 130 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether different types of antidepressant medicines relieve back pain that has lasted at least six months on a daily basis. Study participants will be assigned to treatment with either a antidepressant acting on the serotonin system in the brain (fluoxetine), one acting on the noradrenaline system (desipramine, or to a control medication not expected to relieve pain (benztropine). Each participant will be seen at least nine times during their 12 weeks on medication. This is a phase 2/3, outpatient study.
Interventions
- DRUG Fluoxetine
- DRUG Desipramine
- DRUG Benztropine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 1999-04 |
| Est. Completion | 2004-03 |
| Phase | Phase 2 |
What the finished NCT00018200 record still lists
NCT00018200 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 3 interventions - of which Fluoxetine is the first listed.
NCT00018200 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00018200 about?
NCT00018200 is a clinical study titled "Effect of Antidepressants on Back Pain". The purpose of this study is to determine whether different types of antidepressant medicines relieve back pain that has lasted at least six months on a daily basis. Study participants will be assigned to treatment with either a antidepressant acting on the serotonin system in the brain (fluoxetine)...
What is the current status of trial NCT00018200?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 130 participants. The study started on 1999-04. Estimated completion is 2004-03.
What interventions are being tested in trial NCT00018200?
The interventions under investigation include: Fluoxetine (DRUG), Desipramine (DRUG), Benztropine (DRUG).
Who is sponsoring clinical trial NCT00018200?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00018200's enrollment target sits among peer trials
130 543rd of 2000 higher than 1,448 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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