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NCT00014937 · ClinicalTrials.gov registry record · NA

Simplified Drug Regimens for HIV Patients in ACTG 388 or Patients Who Responded to A First Potent Combination Regimen

A NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
NA
Development phase
240
Enrollment target

NCT00014937: Completed NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00014937 is a NA study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 240 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00014937, a NA study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
NA
Development phase
240 participants
Enrollment target

Study Summary

ACTG 388 was a clinical trial that compared three- and four-drug anti-HIV drug regimens and demonstrated the effectiveness of a three-drug regimen. This study will compare the ability of two different three-drug anti-HIV drug regimens to reduce levels of HIV in the blood. The study will also evaluate whether patients discontinue the regimens because of drug side effects.

Interventions

  • DRUG lamivudine
  • DRUG efavirenz
  • DRUG lopinavir/ritonavir
  • DRUG stavudine
  • DRUG lamivudine/zidovudine

Trial Details

FieldValue
Enrollment Target 240 participants
Phase NA

What the finished NCT00014937 record still lists

NCT00014937 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 5 interventions - of which lamivudine is the first listed.

NCT00014937 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00014937 about?

NCT00014937 is a clinical study titled "Simplified Drug Regimens for HIV Patients in ACTG 388 or Patients Who Responded to A First Potent Combination Regimen". ACTG 388 was a clinical trial that compared three- and four-drug anti-HIV drug regimens and demonstrated the effectiveness of a three-drug regimen. This study will compare the ability of two different three-drug anti-HIV drug regimens to reduce levels of HIV in the blood. The study will also evaluat...

What is the current status of trial NCT00014937?

This trial is currently completed. It is a NA study. The enrollment target is 240 participants.

What interventions are being tested in trial NCT00014937?

The interventions under investigation include: lamivudine (DRUG), efavirenz (DRUG), lopinavir/ritonavir (DRUG), stavudine (DRUG), lamivudine/zidovudine (DRUG).

Who is sponsoring clinical trial NCT00014937?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00014937's enrollment target sits among peer trials

240 440th of 2000 higher than 1,542 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00014937, the US trial registry maintained by the National Library of Medicine. NCT00014937 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.