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NCT00006472 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer

A Phase 2 study, sponsored by Medstar Health Research Institute.

Terminated
Registry status
Phase 2
Development phase
4
Enrollment target

NCT00006472: Clinical Trial Phase 2 study, sponsored by Medstar Health Research Institute.

NCT00006472 is a Phase 2 study that was terminated before completion, run by Medstar Health Research Institute. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00006472, a Phase 2 study, was terminated before completion, sponsored by Medstar Health Research Institute.

TERMINATED
Registry status
Phase 2
Development phase
4 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Giving chemotherapy drugs and radiation therapy before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus radiation therapy given before surgery in treating patients who have stage I, stage II, or stage III esophageal cancer.

Interventions

  • DRUG carboplatin
  • DRUG paclitaxel
  • DRUG fluorouracil
  • PROCEDURE conventional surgery
  • RADIATION radiation therapy

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2000-01
Est. Completion 2002-09-10
Phase Phase 2
Medstar Health Research Institute

115 total trials

Why NCT00006472 stopped before completion

NCT00006472 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 5 interventions - of which carboplatin is the first listed.

NCT00006472 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00006472 about?

NCT00006472 is a clinical study titled "Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Giving chemotherapy drugs and radiation therapy before surgery may shrink the tumor so that it can be removed durin...

What is the current status of trial NCT00006472?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2000-01. Estimated completion is 2002-09-10.

What interventions are being tested in trial NCT00006472?

The interventions under investigation include: carboplatin (DRUG), paclitaxel (DRUG), fluorouracil (DRUG), conventional surgery (PROCEDURE), radiation therapy (RADIATION).

Who is sponsoring clinical trial NCT00006472?

This trial is sponsored by Medstar Health Research Institute, which has 115 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00006472's enrollment target sits among peer trials

4 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00006472, the US trial registry maintained by the National Library of Medicine. NCT00006472 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.