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NCT00006186 · ClinicalTrials.gov registry record · NA
Autologous Fresh Whole Blood and Coagulation Following Cardiopulmonary Bypass in Infants
A NA study, sponsored by National Center for Research Resources (NCRR).
- Completed
- Registry status
- NA
- Development phase
NCT00006186 is a NA study that has completed, run by National Center for Research Resources (NCRR).
The verdict
NCT00006186, a NA study, has completed, sponsored by National Center for Research Resources (NCRR).
- COMPLETED
- Registry status
- NA
- Development phase
Study Summary
Dilution of blood caused by cardiopulmonary bypass (the heart-lung machine) during open heart surgery is associated with decreased concentrations in the blood of coagulation factors. This can be extreme in infants because of their small blood volumes and can lead to impairment of the normal blood clotting mechanism and excessive bleeding after the operation. Transfusion of fresh whole blood has been shown to be an effective treatment because fresh blood is rich in coagulation factors. However, it is difficult to obtain truly fresh blood from a blood bank. We hypothesized that fresh blood drawn from the patient and given back after cardiopulmonary bypass would improve the clotting mechanism. In our study, the infants in the treatment group have some of their own fresh blood removed after they are anesthetized for the operation and before they are placed on cardiopulmonary bypass. This blood is then given back to them after completion of cardiopulmonary bypass. Infants in the control group will not have their own blood removed but will undergo cardiopulmonary bypass. We will compare the two groups by drawing blood samples that measure coagulation tests.
Interventions
- PROCEDURE Autologous fresh whole blood
Trial Details
| Field | Value |
|---|---|
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00006186
The ClinicalTrials.gov registry entry for NCT00006186 describes a study currently listed as completed, categorized as NA. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is National Center for Research Resources (NCRR), which has 94 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Autologous fresh whole blood is the first listed.
NCT00006186 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00006186 about?
NCT00006186 is a clinical study titled "Autologous Fresh Whole Blood and Coagulation Following Cardiopulmonary Bypass in Infants". Dilution of blood caused by cardiopulmonary bypass (the heart-lung machine) during open heart surgery is associated with decreased concentrations in the blood of coagulation factors. This can be extreme in infants because of their small blood volumes and can lead to impairment of the normal blood cl...
What is the current status of trial NCT00006186?
This trial is currently completed. It is a NA study.
What interventions are being tested in trial NCT00006186?
The interventions under investigation include: Autologous fresh whole blood (PROCEDURE).
Who is sponsoring clinical trial NCT00006186?
This trial is sponsored by National Center for Research Resources (NCRR), which has 94 total clinical trials registered on ClinicalTrials.gov.
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