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NCT00005855 · ClinicalTrials.gov registry record · Phase 1
Efaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant Glioma
A Phase 1 study, sponsored by New Approaches to Brain Tumor Therapy Consortium.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT00005855: Completed Phase 1 study, sponsored by New Approaches to Brain Tumor Therapy Consortium.
NCT00005855 is a Phase 1 study that has completed, run by New Approaches to Brain Tumor Therapy Consortium. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00005855, a Phase 1 study, has completed, sponsored by New Approaches to Brain Tumor Therapy Consortium.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of efaproxiral when given with carmustine and to see how well they work in treating patients with progressive or recurrent malignant glioma.
Interventions
- DRUG carmustine
- DRUG efaproxiral
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2000-07 |
| Est. Completion | 2006-10 |
| Phase | Phase 1 |
What the finished NCT00005855 record still lists
NCT00005855 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 2 interventions - of which carmustine is the first listed.
NCT00005855 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00005855 about?
NCT00005855 is a clinical study titled "Efaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant Glioma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of efaproxiral when given with carmustine and to ...
What is the current status of trial NCT00005855?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2000-07. Estimated completion is 2006-10.
What interventions are being tested in trial NCT00005855?
The interventions under investigation include: carmustine (DRUG), efaproxiral (DRUG).
Who is sponsoring clinical trial NCT00005855?
This trial is sponsored by New Approaches to Brain Tumor Therapy Consortium, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00005855's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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