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NCT00005818 · ClinicalTrials.gov registry record · Phase 1
SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer
A Phase 1 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 1
- Development phase
- 68
- Enrollment target
NCT00005818: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).
NCT00005818 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 68 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00005818, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 68 participants
- Enrollment target
Study Summary
Phase I/II trial to study the effectiveness of combining SU5416 and irinotecan in treating patients who have advanced colorectal cancer. SU5416 may stop the growth of colorectal cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die
Primary Outcome
Estimated using the Kaplan-Meier method. Associated 95% confidence intervals will be computed.
Interventions
- OTHER laboratory biomarker analysis
- DRUG irinotecan hydrochloride
- DRUG semaxanib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2000-03 |
| Phase | Phase 1 |
What the finished NCT00005818 record still lists
NCT00005818 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% higher).
The record links to 0 conditions, and to 3 interventions - of which laboratory biomarker analysis is the first listed.
NCT00005818 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00005818 about?
NCT00005818 is a clinical study titled "SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer". Phase I/II trial to study the effectiveness of combining SU5416 and irinotecan in treating patients who have advanced colorectal cancer. SU5416 may stop the growth of colorectal cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividin...
What is the current status of trial NCT00005818?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 68 participants. The study started on 2000-03.
What interventions are being tested in trial NCT00005818?
The interventions under investigation include: laboratory biomarker analysis (OTHER), irinotecan hydrochloride (DRUG), semaxanib (DRUG).
Who is sponsoring clinical trial NCT00005818?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00005818's enrollment target sits among peer trials
68 776th of 2000 higher than 1,219 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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