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NCT00005808 · ClinicalTrials.gov registry record · Phase 1
Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia
A Phase 1 study, sponsored by National Cancer Institute (NCI).
- Terminated
- Registry status
- Phase 1
- Development phase
- 54
- Enrollment target
NCT00005808: Clinical Trial Phase 1 study, sponsored by National Cancer Institute (NCI).
NCT00005808 is a Phase 1 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 54 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00005808, a Phase 1 study, was terminated before completion, sponsored by National Cancer Institute (NCI).
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 54 participants
- Enrollment target
Study Summary
Phase I trial to study the effectiveness of photodynamic therapy with lutetium texaphyrin in treating patients who have cervical intraepithelial neoplasia. Photodynamic therapy uses light and drugs such as lutetium texaphyrin that make abnormal cells more sensitive to light and may kill abnormal cells in the cervix and prevent the development of cervical cancer
Primary Outcome
A simplified graphical analysis will be utilized to determine the drug dose and time after administration that provides the largest differential area between lutein texaphyrin tissue levels in neoplastic and normal cervical tissue
Interventions
- OTHER laboratory biomarker analysis
- DRUG photodynamic therapy
- DRUG motexafin lutetium
- PROCEDURE loop electrosurgical excision procedure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2000-12 |
| Phase | Phase 1 |
Why NCT00005808 stopped before completion
NCT00005808 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% lower).
The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.
NCT00005808 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00005808 about?
NCT00005808 is a clinical study titled "Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia". Phase I trial to study the effectiveness of photodynamic therapy with lutetium texaphyrin in treating patients who have cervical intraepithelial neoplasia. Photodynamic therapy uses light and drugs such as lutetium texaphyrin that make abnormal cells more sensitive to light and may kill abnormal cel...
What is the current status of trial NCT00005808?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 54 participants. The study started on 2000-12.
What interventions are being tested in trial NCT00005808?
The interventions under investigation include: laboratory biomarker analysis (OTHER), photodynamic therapy (DRUG), motexafin lutetium (DRUG), loop electrosurgical excision procedure (PROCEDURE).
Who is sponsoring clinical trial NCT00005808?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00005808's enrollment target sits among peer trials
54 931st of 2000 higher than 1,053 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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