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NCT00005796 · ClinicalTrials.gov registry record · Phase 1
Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
A Phase 1 study, sponsored by Indiana University.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT00005796: Completed Phase 1 study, sponsored by Indiana University.
NCT00005796 is a Phase 1 study that has completed, run by Indiana University. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00005796, a Phase 1 study, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Inserting a specific gene into a person's peripheral stem cells may improve the body's ability to fight cancer or make the cancer more sensitive to chemotherapy. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy plus gene therapy in treating patients who have CNS tumors.
Interventions
- DRUG vincristine sulfate
- DRUG lomustine
- DRUG procarbazine hydrochloride
- BIOLOGICAL gene therapy
- PROCEDURE filgrastim
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2000-02 |
| Est. Completion | 2011-12 |
| Phase | Phase 1 |
What the finished NCT00005796 record still lists
NCT00005796 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 5 interventions - of which vincristine sulfate is the first listed.
NCT00005796 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00005796 about?
NCT00005796 is a clinical study titled "Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Inserting a specific gene into a person's peripheral stem cells may improve the body's ability to fight cancer or make the c...
What is the current status of trial NCT00005796?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2000-02. Estimated completion is 2011-12.
What interventions are being tested in trial NCT00005796?
The interventions under investigation include: vincristine sulfate (DRUG), lomustine (DRUG), procarbazine hydrochloride (DRUG), gene therapy (BIOLOGICAL), filgrastim (PROCEDURE).
Who is sponsoring clinical trial NCT00005796?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00005796's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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