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NCT00005089 · ClinicalTrials.gov registry record · Phase 2

S0014 Combination Chemotherapy Plus Rituximab and Radiation Therapy in Treating Patients With Stage I or Stage II Non-Hodgkin's Lymphoma

A Phase 2 study, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
71
Enrollment target

NCT00005089: Completed Phase 2 study, sponsored by SWOG Cancer Research Network.

NCT00005089 is a Phase 2 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 71 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00005089, a Phase 2 study, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
71 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies, such as rituximab, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Radiation therapy uses high-energy x-rays to damage cancer cells. Combining chemotherapy with monoclonal antibody therapy and radiation therapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus rituximab and radiation therapy in treating patients who have stage I or stage II non-Hodgkin's lymphoma.

Interventions

  • DRUG prednisone
  • DRUG cyclophosphamide
  • BIOLOGICAL rituximab
  • DRUG doxorubicin hydrochloride
  • DRUG vincristine sulfate

Trial Details

FieldValue
Enrollment Target 71 participants
Start Date 2000-04
Est. Completion 2014-04
Phase Phase 2
SWOG Cancer Research Network

270 total trials

What the finished NCT00005089 record still lists

NCT00005089 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 71 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 5 interventions - of which prednisone is the first listed.

NCT00005089 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00005089 about?

NCT00005089 is a clinical study titled "S0014 Combination Chemotherapy Plus Rituximab and Radiation Therapy in Treating Patients With Stage I or Stage II Non-Hodgkin's Lymphoma". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies, such as rituximab, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Radiation therapy...

What is the current status of trial NCT00005089?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 71 participants. The study started on 2000-04. Estimated completion is 2014-04.

What interventions are being tested in trial NCT00005089?

The interventions under investigation include: prednisone (DRUG), cyclophosphamide (DRUG), rituximab (BIOLOGICAL), doxorubicin hydrochloride (DRUG), vincristine sulfate (DRUG).

Who is sponsoring clinical trial NCT00005089?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00005089's enrollment target sits among peer trials

71 936th of 2000 higher than 1,064 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00005089, the US trial registry maintained by the National Library of Medicine. NCT00005089 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.