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NCT00004583 · ClinicalTrials.gov registry record · Phase 3

A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy

A Phase 3 study, sponsored by Abbott.

Completed
Registry status
Phase 3
Development phase
660
Enrollment target

NCT00004583 is a Phase 3 study that has completed, run by Abbott. The registered enrollment target is 660 participants.

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The verdict

NCT00004583, a Phase 3 study, has completed, sponsored by Abbott.

COMPLETED
Registry status
Phase 3
Development phase
660 participants
Enrollment target

Study Summary

The purpose of this study is to see how safe a new protease inhibitor (PI) is and how well it fights HIV infection. A PI is a drug that stops HIV from using healthy cells to make more virus. This study will compare the new PI combination of ABT-378 plus ritonavir (RTV) with another PI, nelfinavir (NFV). Earlier studies suggest ABT-378/RTV will be just as good as and perhaps better than NFV at fighting HIV infection.

Interventions

  • DRUG Lamivudine
  • DRUG Stavudine
  • DRUG Nelfinavir mesylate
  • DRUG Lopinavir/Ritonavir

Trial Details

FieldValue
Enrollment Target 660 participants
Start Date 1999-03
Phase Phase 3

Sponsor

Abbott

181 total trials

What the Registry Record Tells You About NCT00004583

The ClinicalTrials.gov registry entry for NCT00004583 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 660 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abbott, which has 181 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Lamivudine is the first listed.

NCT00004583 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00004583 about?

NCT00004583 is a clinical study titled "A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy". The purpose of this study is to see how safe a new protease inhibitor (PI) is and how well it fights HIV infection. A PI is a drug that stops HIV from using healthy cells to make more virus. This study will compare the new PI combination of ABT-378 plus ritonavir (RTV) with another PI, nelfinavir (N...

What is the current status of trial NCT00004583?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 660 participants. The study started on 1999-03.

What interventions are being tested in trial NCT00004583?

The interventions under investigation include: Lamivudine (DRUG), Stavudine (DRUG), Nelfinavir mesylate (DRUG), Lopinavir/Ritonavir (DRUG).

Who is sponsoring clinical trial NCT00004583?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.