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NCT00004485 · ClinicalTrials.gov registry record · Phase 1
Bone Marrow Transplantation in Treating Children With Sickle Cell Disease
A Phase 1 study, sponsored by Fred Hutchinson Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 50
- Enrollment target
NCT00004485 is a Phase 1 study that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 50 participants.
The verdict
NCT00004485, a Phase 1 study, has completed, sponsored by Fred Hutchinson Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 50 participants
- Enrollment target
Study Summary
RATIONALE: Sickle cell disease is an inherited disorder in which abnormal, crescent-shaped red blood cells interfere with the ability of the blood to carry oxygen through the body and can cause severe pain, stroke, and organ damage. Bone marrow transplantation, is a procedure in which the soft, sponge-like tissue in the center of bones producing white blood cells, red blood cells, and platelets is replaced by bone marrow from a another person. Bone marrow transplantation may be an effective treatment in relieving the symptoms of sickle cell disease. PURPOSE: Phase I/II trial to study the effectiveness of bone marrow transplantation in treating children who have sickle cell disease.
Interventions
- PROCEDURE Bone Marrow Transplantation
- DRUG fludarabine
- DRUG cyclosporine
- DRUG mycophenolate mofetil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 1999-12 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00004485
The ClinicalTrials.gov registry entry for NCT00004485 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Bone Marrow Transplantation is the first listed.
NCT00004485 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00004485 about?
NCT00004485 is a clinical study titled "Bone Marrow Transplantation in Treating Children With Sickle Cell Disease". RATIONALE: Sickle cell disease is an inherited disorder in which abnormal, crescent-shaped red blood cells interfere with the ability of the blood to carry oxygen through the body and can cause severe pain, stroke, and organ damage. Bone marrow transplantation, is a procedure in which the soft, spon...
What is the current status of trial NCT00004485?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 1999-12.
What interventions are being tested in trial NCT00004485?
The interventions under investigation include: Bone Marrow Transplantation (PROCEDURE), fludarabine (DRUG), cyclosporine (DRUG), mycophenolate mofetil (DRUG).
Who is sponsoring clinical trial NCT00004485?
This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.
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