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NCT00004430 · ClinicalTrials.gov registry record · NA
Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization
A NA study of Corneal Neovascularization, sponsored by Medical College of Hampton Roads.
- Completed
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT00004430: Completed NA study of Corneal Neovascularization, sponsored by Medical College of Hampton Roads.
NCT00004430 is a NA study of Corneal Neovascularization that has completed, run by Medical College of Hampton Roads. The registered enrollment target is 150 participants, above the 32-participant average among 3 other Corneal Neovascularization trials with a reported enrollment target (369% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00004430, a NA study of Corneal Neovascularization, has completed, sponsored by Medical College of Hampton Roads.
- COMPLETED
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
OBJECTIVES: I. Demonstrate the safety and efficacy of dihematoporphyrin derivative (DHP) in laser photodynamic therapy (PDT) in patients with corneal neovascularization. II. Document the histopathologic mechanism of action in selected patients undergoing penetrating keratoplasty following PDT therapy for corneal neovascularization. III. Facilitate FDA product approval of DHP as a photosensitizing agent for laser treatment in these patients. IV. Explore the use of this photosensitizer for ocular and cutaneous basal cell and squamous cell carcinoma.
Conditions Studied
Interventions
- DRUG prednisolone
- DRUG Dihematoporphyrin derivative
- PROCEDURE Laser surgery
Study Locations (1)
Virginia
- Eastern Virginia Medical School - Norfolk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 1994-09 |
| Est. Completion | 1998-09 |
| Phase | NA |
What the finished NCT00004430 record still lists
NCT00004430 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 32-participant average among 3 other Corneal Neovascularization trials with a reported enrollment target (369% higher).
The record links to 1 condition, with Corneal Neovascularization appearing as the primary indexed condition, and to 3 interventions - of which prednisolone is the first listed.
NCT00004430 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT00004430 about?
NCT00004430 is a clinical study titled "Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization". OBJECTIVES: I. Demonstrate the safety and efficacy of dihematoporphyrin derivative (DHP) in laser photodynamic therapy (PDT) in patients with corneal neovascularization. II. Document the histopathologic mechanism of action in selected patients undergoing penetrating keratoplasty following PDT ther...
What is the current status of trial NCT00004430?
This trial is currently completed. It is a NA study. The enrollment target is 150 participants. The study started on 1994-09. Estimated completion is 1998-09.
What conditions does trial NCT00004430 study?
This clinical trial studies the following conditions: Corneal Neovascularization.
What interventions are being tested in trial NCT00004430?
The interventions under investigation include: prednisolone (DRUG), Dihematoporphyrin derivative (DRUG), Laser surgery (PROCEDURE).
Who is sponsoring clinical trial NCT00004430?
This trial is sponsored by Medical College of Hampton Roads, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00004430 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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