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NCT00004430 · ClinicalTrials.gov registry record · NA

Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization

A NA study of Corneal Neovascularization, sponsored by Medical College of Hampton Roads.

Completed
Registry status
NA
Development phase
150
Enrollment target
1
Study location

NCT00004430 is a NA study of Corneal Neovascularization that has completed, run by Medical College of Hampton Roads. The registered enrollment target is 150 participants, above the 32-participant average among 3 other Corneal Neovascularization trials with a reported enrollment target (369% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT00004430, a NA study of Corneal Neovascularization, has completed, sponsored by Medical College of Hampton Roads.

COMPLETED
Registry status
NA
Development phase
150 participants
Enrollment target
1
Study location

Study Summary

OBJECTIVES: I. Demonstrate the safety and efficacy of dihematoporphyrin derivative (DHP) in laser photodynamic therapy (PDT) in patients with corneal neovascularization. II. Document the histopathologic mechanism of action in selected patients undergoing penetrating keratoplasty following PDT therapy for corneal neovascularization. III. Facilitate FDA product approval of DHP as a photosensitizing agent for laser treatment in these patients. IV. Explore the use of this photosensitizer for ocular and cutaneous basal cell and squamous cell carcinoma.

Conditions Studied

Interventions

  • DRUG prednisolone
  • DRUG Dihematoporphyrin derivative
  • PROCEDURE Laser surgery

Study Locations (1)

Virginia

  • Eastern Virginia Medical School - Norfolk

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 1994-09
Est. Completion 1998-09
Phase NA

Sponsor

Medical College of Hampton Roads

1 total trials

What the Registry Record Tells You About NCT00004430

The ClinicalTrials.gov registry entry for NCT00004430 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 32-participant average among 3 other Corneal Neovascularization trials with a reported enrollment target (369% higher). The listed sponsor is Medical College of Hampton Roads, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Corneal Neovascularization appearing as the primary indexed condition, and to 3 interventions - of which prednisolone is the first listed.

NCT00004430 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.

Frequently Asked Questions

What is clinical trial NCT00004430 about?

NCT00004430 is a clinical study titled "Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization". OBJECTIVES: I. Demonstrate the safety and efficacy of dihematoporphyrin derivative (DHP) in laser photodynamic therapy (PDT) in patients with corneal neovascularization. II. Document the histopathologic mechanism of action in selected patients undergoing penetrating keratoplasty following PDT ther...

What is the current status of trial NCT00004430?

This trial is currently completed. It is a NA study. The enrollment target is 150 participants. The study started on 1994-09. Estimated completion is 1998-09.

What conditions does trial NCT00004430 study?

This clinical trial studies the following conditions: Corneal Neovascularization.

What interventions are being tested in trial NCT00004430?

The interventions under investigation include: prednisolone (DRUG), Dihematoporphyrin derivative (DRUG), Laser surgery (PROCEDURE).

Who is sponsoring clinical trial NCT00004430?

This trial is sponsored by Medical College of Hampton Roads, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00004430 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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