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NCT00004323 · ClinicalTrials.gov registry record · Phase 2

Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia

A Phase 2 study of Aplastic Anemia, sponsored by National Center for Research Resources (NCRR).

Completed
Registry status
Phase 2
Development phase
10
Enrollment target
1
Study location

NCT00004323: Completed Phase 2 study of Aplastic Anemia, sponsored by National Center for Research Resources (NCRR).

NCT00004323 is a Phase 2 study of Aplastic Anemia that has completed, run by National Center for Research Resources (NCRR). The registered enrollment target is 10 participants, below the 42-participant average among 23 other Aplastic Anemia trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00004323, a Phase 2 study of Aplastic Anemia, has completed, sponsored by National Center for Research Resources (NCRR).

COMPLETED
Registry status
Phase 2
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

OBJECTIVES: I. Evaluate the efficacy of related, HLA-identical bone marrow transplantation following cyclophosphamide (CTX) and antithymocyte globulin in patients with aplastic anemia. II. Evaluate the efficacy of related, HLA-nonidentical bone marrow transplantation following CTX and total-body irradiation/total-lymphoid irradiation in patients with aplastic anemia.

Conditions Studied

Aplastic Anemia

Interventions

  • DRUG cyclophosphamide
  • DRUG methotrexate
  • DRUG mesna
  • DRUG cyclosporine
  • DRUG anti-thymocyte globulin

Study Locations (1)

California

  • Center for Health Sciences - Los Angeles

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 1995-02
Phase Phase 2
National Center for Research Resources (NCRR)

94 total trials

What the finished NCT00004323 record still lists

NCT00004323 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 42-participant average among 23 other Aplastic Anemia trials with a reported enrollment target (76% lower).

The record links to 1 condition, with Aplastic Anemia appearing as the primary indexed condition, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00004323 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT00004323 about?

NCT00004323 is a clinical study titled "Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia". OBJECTIVES: I. Evaluate the efficacy of related, HLA-identical bone marrow transplantation following cyclophosphamide (CTX) and antithymocyte globulin in patients with aplastic anemia. II. Evaluate the efficacy of related, HLA-nonidentical bone marrow transplantation following CTX and total-body ir...

What is the current status of trial NCT00004323?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 1995-02.

What conditions does trial NCT00004323 study?

This clinical trial studies the following conditions: Aplastic Anemia.

What interventions are being tested in trial NCT00004323?

The interventions under investigation include: cyclophosphamide (DRUG), methotrexate (DRUG), mesna (DRUG), cyclosporine (DRUG), anti-thymocyte globulin (DRUG).

Who is sponsoring clinical trial NCT00004323?

This trial is sponsored by National Center for Research Resources (NCRR), which has 94 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00004323 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Aplastic Anemia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00004323's enrollment target sits among peer trials

10 19th of 23 higher than 3 of 23 other Aplastic Anemia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Aplastic Anemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT00004323, the US trial registry maintained by the National Library of Medicine. NCT00004323 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.