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NCT00003958 · ClinicalTrials.gov registry record · Phase 3

Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma

A Phase 3 study, sponsored by Children's Oncology Group.

Completed
Registry status
Phase 3
Development phase
702
Enrollment target

NCT00003958 is a Phase 3 study that has completed, run by Children's Oncology Group. The registered enrollment target is 702 participants.

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The verdict

NCT00003958, a Phase 3 study, has completed, sponsored by Children's Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
702 participants
Enrollment target

Study Summary

This randomized phase III trial is comparing two different combination chemotherapy regimens to see how well each works in treating patients with previously untreated rhabdomyosarcoma or sarcoma. Drugs used in chemotherapy, such as dactinomycin, cyclophosphamide, vincristine, and topotecan, use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective in treating rhabdomyosarcoma.

Interventions

  • DRUG cyclophosphamide
  • PROCEDURE therapeutic conventional surgery
  • RADIATION radiation therapy
  • BIOLOGICAL dactinomycin
  • DRUG vincristine sulfate

Trial Details

FieldValue
Enrollment Target 702 participants
Start Date 2002-09
Phase Phase 3

Sponsor

Children's Oncology Group

342 total trials

What the Registry Record Tells You About NCT00003958

The ClinicalTrials.gov registry entry for NCT00003958 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 702 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Oncology Group, which has 342 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00003958 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00003958 about?

NCT00003958 is a clinical study titled "Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma". This randomized phase III trial is comparing two different combination chemotherapy regimens to see how well each works in treating patients with previously untreated rhabdomyosarcoma or sarcoma. Drugs used in chemotherapy, such as dactinomycin, cyclophosphamide, vincristine, and topotecan, use diff...

What is the current status of trial NCT00003958?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 702 participants. The study started on 2002-09.

What interventions are being tested in trial NCT00003958?

The interventions under investigation include: cyclophosphamide (DRUG), therapeutic conventional surgery (PROCEDURE), radiation therapy (RADIATION), dactinomycin (BIOLOGICAL), vincristine sulfate (DRUG).

Who is sponsoring clinical trial NCT00003958?

This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.