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NCT00003726 · ClinicalTrials.gov registry record · Phase 1

Lepirudin in Treating Patients With Recurrent or Advanced Small Cell Lung Cancer

A Phase 1 study, sponsored by Dartmouth-Hitchcock Medical Center.

Terminated
Registry status
Phase 1
Development phase
1
Enrollment target

NCT00003726: Clinical Trial Phase 1 study, sponsored by Dartmouth-Hitchcock Medical Center.

NCT00003726 is a Phase 1 study that was terminated before completion, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003726, a Phase 1 study, was terminated before completion, sponsored by Dartmouth-Hitchcock Medical Center.

TERMINATED
Registry status
Phase 1
Development phase
1 participants
Enrollment target

Study Summary

RATIONALE: Anticoagulants, such as lepirudin, may help prevent blood clots from forming in patients who have received chemotherapy for small cell lung cancer. PURPOSE: This phase I/II trial is studying the side effects and best dose of lepirudin in treating patients with recurrent or advanced small cell lung cancer.

Primary Outcome

Evaluated through clinical exams, tumor assessments, laboratory assessment, and adverse event assessments.

Interventions

  • BIOLOGICAL lepirudin

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 1998-11
Est. Completion 2001-07
Phase Phase 1
Dartmouth-Hitchcock Medical Center

427 total trials

Why NCT00003726 stopped before completion

NCT00003726 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which lepirudin is the first listed.

NCT00003726 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003726 about?

NCT00003726 is a clinical study titled "Lepirudin in Treating Patients With Recurrent or Advanced Small Cell Lung Cancer". RATIONALE: Anticoagulants, such as lepirudin, may help prevent blood clots from forming in patients who have received chemotherapy for small cell lung cancer. PURPOSE: This phase I/II trial is studying the side effects and best dose of lepirudin in treating patients with recurrent or advanced small...

What is the current status of trial NCT00003726?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 1998-11. Estimated completion is 2001-07.

What interventions are being tested in trial NCT00003726?

The interventions under investigation include: lepirudin (BIOLOGICAL).

Who is sponsoring clinical trial NCT00003726?

This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003726's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003726, the US trial registry maintained by the National Library of Medicine. NCT00003726 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.