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NCT00003594 · ClinicalTrials.gov registry record · Phase 3
Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
A Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,691
- Enrollment target
NCT00003594: Completed Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.
NCT00003594 is a Phase 3 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 1,691 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (119% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003594, a Phase 3 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,691 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is most effective in treating advanced colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of various combination chemotherapy regimens in treating patients who have advanced, recurrent, or metastatic colorectal cancer that cannot be treated with surgery or radiation therapy.
Interventions
- DRUG oxaliplatin
- DRUG fluorouracil
- DRUG leucovorin calcium
- DRUG irinotecan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,691 participants |
| Start Date | 1998-10 |
| Est. Completion | 2004-10 |
| Phase | Phase 3 |
What the finished NCT00003594 record still lists
NCT00003594 is an interventional study that assigns participants to a tested intervention. Its 1,691 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (119% higher).
The record links to 0 conditions, and to 4 interventions - of which oxaliplatin is the first listed.
NCT00003594 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00003594 about?
NCT00003594 is a clinical study titled "Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is most effective in treating advanced colorectal cancer. PUR...
What is the current status of trial NCT00003594?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,691 participants. The study started on 1998-10. Estimated completion is 2004-10.
What interventions are being tested in trial NCT00003594?
The interventions under investigation include: oxaliplatin (DRUG), fluorouracil (DRUG), leucovorin calcium (DRUG), irinotecan (DRUG).
Who is sponsoring clinical trial NCT00003594?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00003594's enrollment target sits among peer trials
1,691 134th of 2000 higher than 1,867 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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