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NCT00003575 · ClinicalTrials.gov registry record · Phase 2

Interleukin-12 Following Chemotherapy in Treating Patients With Refractory HIV-Associated Non-Hodgkin's Lymphoma

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
40
Enrollment target

NCT00003575: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00003575 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003575, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

Phase II trial to compare the effectiveness of interleukin-12 following chemotherapy in treating patients who have refractory HIV-associated non-Hodgkin's lymphoma. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person' white blood cells to kill cancer cells.

Interventions

  • DRUG etoposide
  • DRUG ifosfamide
  • BIOLOGICAL filgrastim
  • BIOLOGICAL recombinant interleukin-12

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 1999-01
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00003575 record still lists

NCT00003575 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 4 interventions - of which etoposide is the first listed.

NCT00003575 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003575 about?

NCT00003575 is a clinical study titled "Interleukin-12 Following Chemotherapy in Treating Patients With Refractory HIV-Associated Non-Hodgkin's Lymphoma". Phase II trial to compare the effectiveness of interleukin-12 following chemotherapy in treating patients who have refractory HIV-associated non-Hodgkin's lymphoma. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interleukin-12 may kill tu...

What is the current status of trial NCT00003575?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 1999-01.

What interventions are being tested in trial NCT00003575?

The interventions under investigation include: etoposide (DRUG), ifosfamide (DRUG), filgrastim (BIOLOGICAL), recombinant interleukin-12 (BIOLOGICAL).

Who is sponsoring clinical trial NCT00003575?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003575's enrollment target sits among peer trials

40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003575, the US trial registry maintained by the National Library of Medicine. NCT00003575 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.