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NCT00003269 · ClinicalTrials.gov registry record · Phase 2
Amifostine Followed by High Dose Chemotherapy in Treating Patients With Hematologic Cancer or Solid Tumors
A Phase 2 study, sponsored by Scripps Health.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
NCT00003269: Completed Phase 2 study, sponsored by Scripps Health.
NCT00003269 is a Phase 2 study that has completed, run by Scripps Health. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003269, a Phase 2 study, has completed, sponsored by Scripps Health.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy. PURPOSE: Randomized phase II trial to study the effectiveness of amifostine followed by high-dose chemotherapy in treating patients with hematologic cancer or solid tumors.
Primary Outcome
number of days absolute neutrophil count less than 500 during the nadir period after administration of high dose chemotherapy
Interventions
- DRUG cisplatin
- DRUG cyclophosphamide
- DRUG etoposide
- BIOLOGICAL sargramostim
- DRUG amifostine trihydrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 1998-02 |
| Est. Completion | 2001-01 |
| Phase | Phase 2 |
What the finished NCT00003269 record still lists
NCT00003269 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 5 interventions - of which cisplatin is the first listed.
NCT00003269 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00003269 about?
NCT00003269 is a clinical study titled "Amifostine Followed by High Dose Chemotherapy in Treating Patients With Hematologic Cancer or Solid Tumors". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy. PURPOSE: Randomized phase II trial to study the effectiveness of amifostin...
What is the current status of trial NCT00003269?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 1998-02. Estimated completion is 2001-01.
What interventions are being tested in trial NCT00003269?
The interventions under investigation include: cisplatin (DRUG), cyclophosphamide (DRUG), etoposide (DRUG), sargramostim (BIOLOGICAL), amifostine trihydrate (DRUG).
Who is sponsoring clinical trial NCT00003269?
This trial is sponsored by Scripps Health, which has 30 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00003269's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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