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NCT00003196 · ClinicalTrials.gov registry record · NA

Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma

A NA study, sponsored by Fred Hutchinson Cancer Center.

Completed
Registry status
NA
Development phase
63
Enrollment target

NCT00003196 is a NA study that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 63 participants.

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The verdict

NCT00003196, a NA study, has completed, sponsored by Fred Hutchinson Cancer Center.

COMPLETED
Registry status
NA
Development phase
63 participants
Enrollment target

Study Summary

This pilot clinical trial studies low-dose total body irradiation and donor peripheral blood stem cell transplant followed by donor lymphocyte infusion in treatment patients with non-Hodgkin lymphoma, chronic lymphocytic leukemia, or multiple myeloma. Giving total-body irradiation before a donor peripheral blood stem cell transplant helps stop the growth of cells in the bone marrow, including normal blood-forming cells (stem cells) and cancer cells. When healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Once the donated stem cells begin working, the patient's immune system may see the remaining cancer cells as not belonging in the patient's body and destroy them. Giving an infusion of the donor's white blood cells (donor lymphocyte infusion) may boost this effect.

Interventions

  • PROCEDURE peripheral blood stem cell transplantation
  • DRUG chemotherapy
  • DRUG cyclosporine
  • RADIATION total-body irradiation
  • DRUG mycophenolate mofetil

Trial Details

FieldValue
Enrollment Target 63 participants
Start Date 1997-09
Est. Completion 2002-04
Phase NA

Sponsor

Fred Hutchinson Cancer Center

483 total trials

What the Registry Record Tells You About NCT00003196

The ClinicalTrials.gov registry entry for NCT00003196 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 63 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which peripheral blood stem cell transplantation is the first listed.

NCT00003196 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00003196 about?

NCT00003196 is a clinical study titled "Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma". This pilot clinical trial studies low-dose total body irradiation and donor peripheral blood stem cell transplant followed by donor lymphocyte infusion in treatment patients with non-Hodgkin lymphoma, chronic lymphocytic leukemia, or multiple myeloma. Giving total-body irradiation before a donor per...

What is the current status of trial NCT00003196?

This trial is currently completed. It is a NA study. The enrollment target is 63 participants. The study started on 1997-09. Estimated completion is 2002-04.

What interventions are being tested in trial NCT00003196?

The interventions under investigation include: peripheral blood stem cell transplantation (PROCEDURE), chemotherapy (DRUG), cyclosporine (DRUG), total-body irradiation (RADIATION), mycophenolate mofetil (DRUG).

Who is sponsoring clinical trial NCT00003196?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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