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NCT00003187 · ClinicalTrials.gov registry record · Phase 2

Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma

A Phase 2 study, sponsored by Virginia Commonwealth University.

Completed
Registry status
Phase 2
Development phase
19
Enrollment target

NCT00003187: Completed Phase 2 study, sponsored by Virginia Commonwealth University.

NCT00003187 is a Phase 2 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 19 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003187, a Phase 2 study, has completed, sponsored by Virginia Commonwealth University.

COMPLETED
Registry status
Phase 2
Development phase
19 participants
Enrollment target

Study Summary

RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill cancer cells. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Eliminating the T cells from the donor cells before transplanting them may prevent this from happening. PURPOSE: Randomized phase II/III trial to compare the effectiveness of conventional bone marrow transplantation with T cell-depleted bone marrow transplantation in treating patients who have leukemia, myelodysplasia, or lymphoblastic lymphoma.

Interventions

  • DRUG cyclophosphamide
  • DRUG methotrexate
  • BIOLOGICAL filgrastim
  • DRUG cytarabine
  • DRUG cyclosporine

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 1995-05
Est. Completion 2005-02
Phase Phase 2
Virginia Commonwealth University

558 total trials

What the finished NCT00003187 record still lists

NCT00003187 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00003187 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003187 about?

NCT00003187 is a clinical study titled "Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma". RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill cancer cells. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Eliminating the T cells from the d...

What is the current status of trial NCT00003187?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 1995-05. Estimated completion is 2005-02.

What interventions are being tested in trial NCT00003187?

The interventions under investigation include: cyclophosphamide (DRUG), methotrexate (DRUG), filgrastim (BIOLOGICAL), cytarabine (DRUG), cyclosporine (DRUG).

Who is sponsoring clinical trial NCT00003187?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003187's enrollment target sits among peer trials

19 1894th of 2000 higher than 103 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003187, the US trial registry maintained by the National Library of Medicine. NCT00003187 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.