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NCT00003068 · ClinicalTrials.gov registry record · Phase 2

High-Dose Chemotherapy and Autologous Blood Cell Transplantation in Treating Patients With Primary, Locally Advanced, or Stage IV Breast Cancer

A Phase 2 study, sponsored by University of Arizona.

Completed
Registry status
Phase 2
Development phase
30
Enrollment target

NCT00003068: Completed Phase 2 study, sponsored by University of Arizona.

NCT00003068 is a Phase 2 study that has completed, run by University of Arizona. The registered enrollment target is 30 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003068, a Phase 2 study, has completed, sponsored by University of Arizona.

COMPLETED
Registry status
Phase 2
Development phase
30 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of high-dose mitoxantrone, thiotepa, and cyclophosphamide plus autologous peripheral stem cell transplantation and amifostine in treating patients with primary, locally advanced, or stage IV breast cancer.

Interventions

  • DRUG cyclophosphamide
  • PROCEDURE peripheral blood stem cell transplantation
  • DRUG thiotepa
  • DRUG amifostine trihydrate
  • DRUG mitoxantrone hydrochloride

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 1997-06
Est. Completion 2002-11
Phase Phase 2
University of Arizona

349 total trials

What the finished NCT00003068 record still lists

NCT00003068 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00003068 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003068 about?

NCT00003068 is a clinical study titled "High-Dose Chemotherapy and Autologous Blood Cell Transplantation in Treating Patients With Primary, Locally Advanced, or Stage IV Breast Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. PURPOSE: Phase II trial to st...

What is the current status of trial NCT00003068?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 1997-06. Estimated completion is 2002-11.

What interventions are being tested in trial NCT00003068?

The interventions under investigation include: cyclophosphamide (DRUG), peripheral blood stem cell transplantation (PROCEDURE), thiotepa (DRUG), amifostine trihydrate (DRUG), mitoxantrone hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00003068?

This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003068's enrollment target sits among peer trials

30 1582nd of 2000 higher than 332 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003068, the US trial registry maintained by the National Library of Medicine. NCT00003068 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.