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NCT00002882 · ClinicalTrials.gov registry record · Phase 3

Interferon Alfa With or Without Combination Chemotherapy Plus Interleukin-2 in Treating Patients With Melanoma

A Phase 3 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 3
Development phase
140
Enrollment target

NCT00002882: Completed Phase 3 study, sponsored by M.D. Anderson Cancer Center.

NCT00002882 is a Phase 3 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 140 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002882, a Phase 3 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 3
Development phase
140 participants
Enrollment target

Study Summary

RATIONALE: Interferon alfa may interfere with the growth of cancer cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells. It is not yet known whether interferon alfa plus combination chemotherapy and interleukin-2 is more effective than interferon alfa alone in treating patients with melanoma. PURPOSE: Randomized phase III trial to compare the effectiveness of interferon alfa with or without combination chemotherapy plus interleukin-2 in treating patients with melanoma.

Interventions

  • DRUG Cisplatin
  • DRUG Dacarbazine
  • DRUG Vinblastine
  • BIOLOGICAL Aldesleukin (IL-2)
  • BIOLOGICAL Recombinant Interferon Alfa (IFN-A)

Trial Details

FieldValue
Enrollment Target 140 participants
Start Date 1995-11
Est. Completion 2006-04
Phase Phase 3
M.D. Anderson Cancer Center

2,692 total trials

What the finished NCT00002882 record still lists

NCT00002882 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 5 interventions - of which Cisplatin is the first listed.

NCT00002882 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002882 about?

NCT00002882 is a clinical study titled "Interferon Alfa With or Without Combination Chemotherapy Plus Interleukin-2 in Treating Patients With Melanoma". RATIONALE: Interferon alfa may interfere with the growth of cancer cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells. It is not yet known whether interferon alfa plus combination chemotherapy and interleukin-2 is more effective than interferon alfa alone in treat...

What is the current status of trial NCT00002882?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 140 participants. The study started on 1995-11. Estimated completion is 2006-04.

What interventions are being tested in trial NCT00002882?

The interventions under investigation include: Cisplatin (DRUG), Dacarbazine (DRUG), Vinblastine (DRUG), Aldesleukin (IL-2) (BIOLOGICAL), Recombinant Interferon Alfa (IFN-A) (BIOLOGICAL).

Who is sponsoring clinical trial NCT00002882?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002882's enrollment target sits among peer trials

140 1565th of 2000 higher than 424 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002882, the US trial registry maintained by the National Library of Medicine. NCT00002882 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.