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NCT00002849 · ClinicalTrials.gov registry record · Phase 2

S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis

A Phase 2 study, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
93
Enrollment target

NCT00002849: Completed Phase 2 study, sponsored by SWOG Cancer Research Network.

NCT00002849 is a Phase 2 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 93 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002849, a Phase 2 study, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
93 participants
Enrollment target

Study Summary

RATIONALE: Chemotherapy plus interferon alfa may be effective for primary systemic amyloidosis. PURPOSE: Phase II trial to study the effectiveness of dexamethasone plus interferon alfa in treating patients who have primary systemic amyloidosis.

Primary Outcome

50% or more reduction in quantitative immunoglobulin, or if the patient has light-chain disease only, a 50% or more reduction in the urine M-component (Bence-Jones protein).

Interventions

  • DRUG dexamethasone
  • BIOLOGICAL recombinant interferon alfa

Trial Details

FieldValue
Enrollment Target 93 participants
Start Date 1996-11
Est. Completion 2000-07
Phase Phase 2
SWOG Cancer Research Network

270 total trials

What the finished NCT00002849 record still lists

NCT00002849 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 93 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (30% lower).

The record links to 0 conditions, and to 2 interventions - of which dexamethasone is the first listed.

NCT00002849 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002849 about?

NCT00002849 is a clinical study titled "S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis". RATIONALE: Chemotherapy plus interferon alfa may be effective for primary systemic amyloidosis. PURPOSE: Phase II trial to study the effectiveness of dexamethasone plus interferon alfa in treating patients who have primary systemic amyloidosis.

What is the current status of trial NCT00002849?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 93 participants. The study started on 1996-11. Estimated completion is 2000-07.

What interventions are being tested in trial NCT00002849?

The interventions under investigation include: dexamethasone (DRUG), recombinant interferon alfa (BIOLOGICAL).

Who is sponsoring clinical trial NCT00002849?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002849's enrollment target sits among peer trials

93 766th of 2000 higher than 1,234 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002849, the US trial registry maintained by the National Library of Medicine. NCT00002849 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.