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NCT00002819 · ClinicalTrials.gov registry record · Phase 3

Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Persistent Ovarian Epithelial Cancer

A Phase 3 study, sponsored by Gynecologic Oncology Group.

Terminated
Registry status
Phase 3
Development phase

NCT00002819: Clinical Trial Phase 3 study, sponsored by Gynecologic Oncology Group.

NCT00002819 is a Phase 3 study that was terminated before completion, run by Gynecologic Oncology Group. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002819, a Phase 3 study, was terminated before completion, sponsored by Gynecologic Oncology Group.

TERMINATED
Registry status
Phase 3
Development phase

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill tumor cells. It is not yet known whether chemotherapy alone is more effective than chemotherapy plus peripheral stem cell transplantation for ovarian epithelial cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of paclitaxel and carboplatin with that of carboplatin, mitoxantrone, and cyclophosphamide followed by peripheral stem cell transplantation in treating patients who have persistent stage III or stage IV ovarian epithelial cancer.

Interventions

  • DRUG carboplatin
  • DRUG cyclophosphamide
  • DRUG paclitaxel
  • PROCEDURE autologous bone marrow transplantation
  • DRUG mitoxantrone hydrochloride

Trial Details

FieldValue
Start Date 1996-11
Phase Phase 3
Gynecologic Oncology Group

154 total trials

Why NCT00002819 stopped before completion

NCT00002819 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.

The record links to 0 conditions, and to 5 interventions - of which carboplatin is the first listed.

NCT00002819 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002819 about?

NCT00002819 is a clinical study titled "Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Persistent Ovarian Epithelial Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill tumor cells. It is not yet known whet...

What is the current status of trial NCT00002819?

This trial is currently terminated. It is a Phase 3 study. The study started on 1996-11.

What interventions are being tested in trial NCT00002819?

The interventions under investigation include: carboplatin (DRUG), cyclophosphamide (DRUG), paclitaxel (DRUG), autologous bone marrow transplantation (PROCEDURE), mitoxantrone hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00002819?

This trial is sponsored by Gynecologic Oncology Group, which has 154 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT00002819, the US trial registry maintained by the National Library of Medicine. NCT00002819 (unsized enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.