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NCT00002587 · ClinicalTrials.gov registry record · Phase 1

Paclitaxel Plus Topotecan in Treating Patients With Solid Tumors

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT00002587: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00002587 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00002587, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

Phase I trial to study the effectiveness of paclitaxel plus topotecan in treating patients who have solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.

Interventions

  • DRUG paclitaxel
  • DRUG topotecan hydrochloride

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 1994-09
Est. Completion 2000-12
Phase Phase 1
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00002587 record still lists

NCT00002587 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 2 interventions - of which paclitaxel is the first listed.

NCT00002587 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002587 about?

NCT00002587 is a clinical study titled "Paclitaxel Plus Topotecan in Treating Patients With Solid Tumors". Phase I trial to study the effectiveness of paclitaxel plus topotecan in treating patients who have solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.

What is the current status of trial NCT00002587?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 1994-09. Estimated completion is 2000-12.

What interventions are being tested in trial NCT00002587?

The interventions under investigation include: paclitaxel (DRUG), topotecan hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00002587?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002587's enrollment target sits among peer trials

20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002587, the US trial registry maintained by the National Library of Medicine. NCT00002587 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.