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NCT00002463 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 2
Development phase
4
Enrollment target

NCT00002463: Completed Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT00002463 is a Phase 2 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002463, a Phase 2 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
4 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of methotrexate, mechlorethamine, vincristine, procarbazine, and prednisone in treating children with astrocytomas or primitive neuroectodermal tumors.

Interventions

  • DRUG Prednisone
  • DRUG Leucovorin Calcium
  • DRUG Methotrexate
  • DRUG MOPP Regimen
  • DRUG Mechlorethamine Hydrochloride

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 1989-02
Est. Completion 2008-01
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What the finished NCT00002463 record still lists

NCT00002463 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 5 interventions - of which Prednisone is the first listed.

NCT00002463 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002463 about?

NCT00002463 is a clinical study titled "Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of methotrexate, mechlorethamine, vincristine, procarbazine, and prednis...

What is the current status of trial NCT00002463?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 1989-02. Estimated completion is 2008-01.

What interventions are being tested in trial NCT00002463?

The interventions under investigation include: Prednisone (DRUG), Leucovorin Calcium (DRUG), Methotrexate (DRUG), MOPP Regimen (DRUG), Mechlorethamine Hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00002463?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002463's enrollment target sits among peer trials

4 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002463, the US trial registry maintained by the National Library of Medicine. NCT00002463 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.